{"id":3980,"date":"2024-11-01T19:03:46","date_gmt":"2024-11-01T19:03:46","guid":{"rendered":"https:\/\/academicsolidarity.com\/?p=3980"},"modified":"2024-11-09T17:02:41","modified_gmt":"2024-11-09T17:02:41","slug":"anne-sutunun-onemini-artiran-onemli-bir-kesif-mikrorna-arastirmalarina-nobel-odulu","status":"publish","type":"post","link":"https:\/\/academicsolidarity.com\/?p=3980&lang=tr","title":{"rendered":"Anne S\u00fct\u00fcn\u00fcn \u00d6nemini Art\u0131ran \u00d6nemli Bir Ke\u015fif: mikroRNA Ara\u015ft\u0131rmalar\u0131na Nobel \u00d6d\u00fcl\u00fc"},"content":{"rendered":"\n

Nobel Fizyoloji veya T\u0131p \u00d6d\u00fcl\u00fc’ne lay\u0131k g\u00f6r\u00fclen mikroRNA (miRNA) ara\u015ft\u0131rmalar\u0131 alan\u0131ndaki yeni bulgular, bu molek\u00fcllerin anne s\u00fct\u00fcndeki potansiyel rol\u00fcne ve bunlar\u0131n \u00e7ocuk geli\u015fimi a\u00e7\u0131s\u0131ndan olas\u0131 \u00f6nemine yeni bir \u0131\u015f\u0131k tutuyor. MiRNA’lar, haberci RNA’ya (mRNA) ba\u011flanarak ve i\u015flevlerini bloke ederek gen ifadesinin transkripsiyon sonras\u0131 d\u00fczenlenmesinde anahtar rol oynayan k\u0131sa RNA dizileridir. Ba\u015flang\u0131\u00e7ta model organizmalarda yap\u0131lan bu ke\u015fif, insanlar da dahil olmak \u00fczere geni\u015f kapsaml\u0131 \u00e7\u0131kar\u0131mlara sahip.<\/p>\n\n\n\n

miRNA’lar insan anne s\u00fct\u00fcnde bol miktarda bulunur. Witten\/Herdecke \u00dcniversitesi’nden Prof. Dr. Jan Postberg<\/a> gibi ara\u015ft\u0131rmac\u0131lar miRNA\u2019lar\u0131n i\u015flevlerini ara\u015ft\u0131r\u0131yor. Yeni bulgular \u0131\u015f\u0131\u011f\u0131nda anne s\u00fct\u00fcndeki miRNA’lar\u0131n bebe\u011fin ba\u011f\u0131\u015f\u0131kl\u0131k sistemi ve mikrobiyomunun geli\u015fiminde \u00f6nemli bir rol oynayabilece\u011fi hipotezi giderek daha fazla ilgi g\u00f6r\u00fcyor.<\/p>\n\n\n\n

Bu ara\u015ft\u0131rmalar, anne s\u00fct\u00fcn\u00fcn neden s\u0131kl\u0131kla yenido\u011fanlar i\u00e7in en iyi besin olarak kabul edildi\u011fini a\u00e7\u0131klayabilir. Anne s\u00fct\u00fc sadece besinleri de\u011fil ayn\u0131 zamanda sa\u011fl\u0131kl\u0131 geli\u015fimi destekleyen biyoaktif bile\u015fenleri de i\u00e7eriyor. MiRNA’lar\u0131n varl\u0131\u011f\u0131, basit beslenmenin \u00f6tesine ge\u00e7en epigenetik d\u00fczenlemeyi m\u00fcmk\u00fcn k\u0131labilir.<\/p>\n\n\n\n

Di\u011fer taraftan, baz\u0131 k\u00fclt\u00fcrlerde aralar\u0131nda kan ba\u011f\u0131 olmasa da ayn\u0131 kad\u0131n taraf\u0131ndan emzirilen \u00e7ocuklar “s\u00fct karde\u015fi”<\/a> olarak kabul edilir. Bu uygulama, anne s\u00fct\u00fc yoluyla payla\u015f\u0131lan beslenmenin, genetik ba\u011fl\u0131l\u0131\u011f\u0131n \u00f6tesine ge\u00e7en bi\u00e7imlendirici ve birle\u015ftirici bir etkiye sahip oldu\u011funa dair k\u00f6kl\u00fc inanc\u0131n alt\u0131n\u0131 \u00e7izmektedir. MiRNA’n\u0131n anne s\u00fct\u00fcndeki rol\u00fcn\u00fcn giderek daha iyi anla\u015f\u0131lmas\u0131, bir g\u00fcn yenido\u011fanlar\u0131n sa\u011fl\u0131\u011f\u0131n\u0131 ve geli\u015fimini daha da iyile\u015ftirmek i\u00e7in yeni terap\u00f6tik stratejilerin geli\u015ftirilmesine yol a\u00e7abilir. Bu geli\u015fmeler, antik uygulamalar\u0131n modern bilim arac\u0131l\u0131\u011f\u0131yla nas\u0131l yeni bir tan\u0131nma buldu\u011funu g\u00f6steren heyecan verici bir biyomedikal geli\u015fme olarak g\u00f6r\u00fclebilir.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nobel Fizyoloji veya T\u0131p \u00d6d\u00fcl\u00fc’ne lay\u0131k g\u00f6r\u00fclen mikroRNA (miRNA) ara\u015ft\u0131rmalar\u0131 alan\u0131ndaki yeni bulgular, bu molek\u00fcllerin anne s\u00fct\u00fcndeki potansiyel rol\u00fcne ve bunlar\u0131n \u00e7ocuk geli\u015fimi a\u00e7\u0131s\u0131ndan olas\u0131 \u00f6nemine yeni bir \u0131\u015f\u0131k tutuyor. MiRNA’lar, haberci RNA’ya (mRNA) ba\u011flanarak ve i\u015flevlerini bloke ederek gen ifadesinin transkripsiyon sonras\u0131 d\u00fczenlenmesinde anahtar rol oynayan k\u0131sa RNA dizileridir. Ba\u015flang\u0131\u00e7ta model organizmalarda yap\u0131lan bu […]<\/p>\n","protected":false},"author":3,"featured_media":4001,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[114],"tags":[],"class_list":["post-3980","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-guncel"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/academicsolidarity.com\/wp-content\/uploads\/2024\/11\/20241027Mirna-1.png?fit=977%2C977&ssl=1","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=\/wp\/v2\/posts\/3980","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3980"}],"version-history":[{"count":1,"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=\/wp\/v2\/posts\/3980\/revisions"}],"predecessor-version":[{"id":3981,"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=\/wp\/v2\/posts\/3980\/revisions\/3981"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=\/wp\/v2\/media\/4001"}],"wp:attachment":[{"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3980"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3980"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/academicsolidarity.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3980"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}